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Ketamine, Esketamine for Depression and Addiction

Updated: Oct 13

Ketamine, originally developed as an anesthetic, has gained attention in recent years for its potential therapeutic effects in treating depression and certain other mental health conditions. However, it also has a potential for misuse and addiction.


Here are some key points regarding ketamine and its relationship with addiction:

  1. Mechanism of Action: Ketamine works on the NMDA receptor and influences glutamate, a neurotransmitter associated with mood regulation. Its rapid-acting antidepressant effects have made it popular in some clinical settings.

  2. Potential for Misuse: Although ketamine can be effective for some individuals, it is also misused recreationally for its dissociative and hallucinogenic effects. This can lead to patterns of abuse and potential addiction.

  3. Addiction Risk Factors: Those with a history of substance use disorders may be at higher risk for ketamine misuse. The euphoric and dissociative effects can be appealing, particularly to individuals seeking escapism.

  4. Withdrawal Symptoms: While ketamine is not considered physically addictive in the same way as opioids or alcohol, individuals can develop psychological dependence. Some may experience cravings or psychological distress when not using the drug.

  5. Treatment Context: When used therapeutically, ketamine is administered in controlled settings, often in combination with psychotherapy. This approach aims to minimize the risks of misuse and maximize therapeutic benefits.

  6. Research and Regulation: Ongoing research is examining the long-term effects of ketamine use, both in therapeutic and recreational contexts. Regulatory frameworks are also evolving to ensure safe use in clinical settings.

  7. Support and Treatment: For those struggling with ketamine misuse or addiction, seeking professional help is important. Treatment options may include therapy, support groups, and other interventions to address underlying issues.




If you or someone you know is dealing with ketamine misuse or addiction, reaching out for professional support can be a crucial step toward recovery. Please contact The Epec Clinic 443-559-8354 for Botox injections, Esketamine appointments, and suboxone rehabilitation.

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